BAT-25 and BAT-26, two mononucleotide microsatellites, are not sensitive markers of microsatellite instability in acute myeloid leukaemia
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چکیده
منابع مشابه
Usefulness of the mononucleotide marker "BAT-26" for identification of microsatellite instability in colorectal cancers.
s Kulkarni et al, 2010 45 (8.46) 24 21 22 (48.8) 18 (40.0) 5 (11.2) NA NA Case reports Bhatti et al, 2010 1 10 1 (gut) 1 yes died Kulkarni et al, 2009 1 5 1 (O) 1 yes lost Radhakrishnan et al, 2009 1 10 1 1 yes died Wadhwa et al, 2007 1 4 1(+O) 1 yes NA Naithani et al, 2006 1 1 (O) 1 yes alive! Padmanjali et al, 2004 1 6 1 (bone) 1 no lost Geetha et al, 1999 1 4 1& 1 yes died Lodha et al, 1998 ...
متن کاملبررسی وضعیت میکروساتلایتی دو مارکر BAT-26 و BAT-25 با استفاده از دو تکنیک Real Time PCR و HPLC در سرطان کولورکتال
Background: Colorectal Cancer (CRC) is the third common cancer in the world. One of the pathways in colorectal tumor genesis is Microsatellite Instability (MSI+). MSI is detected in about 15% of all colorectal cancers. Colorectal tumors with MSI have dis-tinctive features compared with Microsatellite Stable (MSS) tumors. Due to the high percentage of MSI+ in patients with CRC in Iran, screening...
متن کاملDetection of Microsatellite Instability by High-Resolution Melting Analysis in Colorectal Cancer
Background: Colorectal cancer (CRC) is the third most common cancer worldwide. microsatellite instability (MSI) is a molecular marker of a deficient mismatch repair system and happens in almost 15% of CRCs. Because of a wide frequency of MSI+ CRC in Iran compared to other parts of the world, the importance of screening for this type of cancer is highlighted. Methods: The most common MSI detecti...
متن کاملphylogeography and genetic diversity of the lesser mouse- eared bat (myotis blythii) in iran
in current study, 63 samples of bat populations collected from differ regions were used for evaluating the geographic variations. twenty cranial and dental characters for traditional morphometric and landmarks method on the ventral, dorsal skull and mandible for geometry morphometric studies were used. statistical analyses of traditional morphometric and geometry morphometric data indicated low...
Frequent MSI mononucleotide markers for diagnosis of hereditary nonpolyposis colorectal cancer.
BACKGROUND Failure in the DNA mismatch repair system is commonly accompanied by microsatellite instability and leads to colorectal cancer. The aim of this study was to find the most frequent of five mononucleotide markers in order to devise the simplest diagnostic strategy for identification of patients with hereditary nonpolyposis colorectal cancer (HNPCC) who were defined by defects in mismat...
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ژورنال
عنوان ژورنال: British Journal of Haematology
سال: 2003
ISSN: 0007-1048
DOI: 10.1046/j.1365-2141.2003.04750.x